KMID : 0387720180290010059
|
|
Korean Journal of Blood Transfusion 2018 Volume.29 No. 1 p.59 ~ p.67
|
|
Reduction Plan of ¡®Undeterminable¡¯ in the Unexpected Antibody Screening by the Microcolumn Agglutination Automated Instrument
|
|
Lee Dae-Dong
Kim Dae-Seong Kim Dong-Wook Lee Myung-Hwan Kim On-Jeong Kim Hee-Dong Huh Kwang Lee Mi-Kyung
|
|
Abstract
|
|
|
Background: Among the results of an unexpected antibody screening test using IH-1000, ¡®undeterminable¡¯ results can be obtained. Repeated tests not only use reagents and consumables but also cause a turnaround time delay. Therefore, it is important to reduce the ¡®undeterminable¡¯ results and to determine the effects.
Methods: From January to early June, 2016, 2,872 cases/259,455 tests (1.11%) of ¡®undeterminable¡¯ were detected in the screening test. The factors considered to affect the ¡®undeterminable¡¯ were classified into four categories: ¨ç reagent, ¨è consumables, ¨é inspection environment & specimen, and ¨ê enhancing the equipment management. For data comparison, a chi-square test was conducted (95% confidence interval, 0.05 significant level).
Results: The incidence of ¡®undeterminable¡¯ cases decreased from 1.11% before management to 0.66% (P<0.001) after Pool Cells management. The consumption of ¡®LISS/Coombs Card¡¯ decreased from 1.07% before management to 0.51% (P<0.001) after management. By maintaining a clean inspection environment and strengthening sample management, the rate decreased from 1.11% before management to 0.66% (P<0.001) after management. On the other hand, there was no difference in the incidence of ¡®undeterminable¡¯ between before and after IH-1000 management reinforcement.
Conclusion: Among the factors predicted to affect the decrease in the incidence of ¡®undeterminable¡¯, the management of Pool Cells and keeping the inspection environment clean as well as improving sample management contributed the most to the reduced ¡®undeterminable¡¯. Improvements in the management of consumables, and removing dust from the inside of the equipment, had a positive impact. A continuous quality improvement theme has been adopted and it is helpful for managing and improving the predicted factors.
|
|
KEYWORD
|
|
Unexpected antibody screening, Undeterminable E, Turnaround time
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|
|